PDF BookBiochips as Pathways to Drug Discovery (Drug Discovery Series)

Free Biochips as Pathways to Drug Discovery (Drug Discovery Series)

Free Biochips as Pathways to Drug Discovery (Drug Discovery Series)

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Book Details :
Published on: 2006-10-19
Released on: 2006-10-19
Original language:

In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as biochips to reduce the cost of drug discovery and improve drug safety. The book explores the tools and skills required at each step of the discovery process when using biochips to determine biological outcomes. The authors provide an in-depth review of the clinical and pharmacogenomic relevance of biochips, ChIP-chip assays, and high-throughput approaches. They discuss how biochips are used to develop biomarkers in the drug discovery process, primarily for gene expression profiling and Single Nucleotide Polymorphism (SNP) analysis. The book includes coverage of experimental theory, quality control, clinical laboratory sampling considerations, database concepts, industrial laboratory design, and the analysis of the resultant large data sets. It discusses the application of biochips to the study of malaria, toxicogenomics, and SNPs, as well as intellectual property and market overviews. The book concludes with a comprehensive overview of how these chips are employed from early target discovery through preclinical toxicology and on through to pharmacogenomic and proof of concept studies in humans. Written in an easily accessible style, the breadth of coverage introduces the subject to those new to the field, while the depth of coverage forms a foundation for future work. The book gives you the knowledge required to leverage the technology into bona fide discoveries.Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry. Proteomics Conference 2017 Paris Europe USA Mass ... About Conference. Conference Series LLC like to take this opportunity to welcome all of you to 9 th International Conference & Expo on Proteomics which is to be ... Click Chemistry Publications - Scripps Research Institute 937: Zhang Y.-H.; Gao Z.-X.; Zhong C.-L.; Zhou H.-B.; Chen L.; Wu W.-M.; Peng X.-J.; Yao Z.-J. An Inexpensive Fluorescent Labeling Protocol for Bioactive ... [ihtik.lib.ru] _. [ihtik.lib.ru] _. . : 8094 : 1116 GB; Activating Mutations in the Epidermal Growth Factor ... Methods. We searched for mutations in the EGFR gene in primary tumors from patients with nonsmall-cell lung cancer who had a response to gefitinib those who did ... NanoTemper Technologies GmbH: Monolith NT.115 Series "As part of our drug discovery projects we use Microscale Thermophoresis (MST) as an orthogonal method to measure the binding affinity of compounds to their protein ... COST COST Countries COST Countries. COST is an intergovernmental framework consisting in 36 Member Countries and a Cooperating State. This allows researchers from these countries to ... Glossary of Laboratory Diagnostic Terms - Lab Tests Blog Accuracy. Agreement between your test result value and the true value; i.e. how correct your result is. Affinity. An attractive force between substances or particles ... Drug-Induced Vascular InjuryA Search for Biomarkers Drug-Induced Vascular InjuryA Search for Biomarkers . Discussion Document for the NonClinical Studies Subcommittee. of the Advisory Committee on Pharmaceutical Science Conference Series LLC USA Europe Asia Australia ... 8th International Conference On Medicinal Chemistry & Computer Aided Drug Designing And Smart Drug Delivery Integrative Biology Conference Biology Conferences ... About Conference. Conference Series Ltd invites participants from all over the world to 5 th International Conference on Integrative Biology (Integrative Biology 2017 ...
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